Dernières publications

Publication de diverses études scientifiques

08 - Janvier - 2023

Ivacaftor-Mediated Potentiation of ABCB4 Missense Mutations Affecting Critical Motifs of the NBDs: Repositioning Perspectives for Hepatobiliary Diseases (Équipe Gautheron/Housset)

Int J Mol Sci. 2023 Jan 8;24(2):1236 ABCB4 (ATP-binding cassette subfamily B member 4) is a hepatocanalicular floppase involved in biliary phosphatidylcholine (PC) secretion. Variations in...

29 - Décembre - 2022

Maintenance of methylation profile in imprinting control regions in human induced pluripotent stem cells (Équipe Netchine)

Clin Epigenetics 2022; 14: 190. BACKGROUND : Parental imprinting is an epigenetic mechanism that leads to monoallelic expression of a subset of genes depending on their parental origin....

22 - Décembre - 2022

Fibroblast growth factor-2 bound to specific dermal fibroblast-derived extracellular vesicles is protected from degradation (Équipe Prunier)

Sci Rep 2022 Vol. 12 Issue 1 Pages 22131 Fibroblast growth factor-2 (FGF2) has multiple roles in cutaneous wound healing but its natural low stability prevents the development of its use in...

06 - Décembre - 2022

Interference with Lipoprotein Maturation Sensitizes Methicillin-Resistant Staphylococcus aureus to Human Group IIA-Secreted Phospholipase A2 and Daptomycin (Équipe Corvol)

J Innate Immun. 2022 Dec 6:1-18 Methicillin-resistant Staphylococcus aureus (MRSA) has been classified as a high priority pathogen by the World Health Organization underlining the high...

06 - Décembre - 2022

Impact of IBD-Associated Dysbiosis on Bacterial Quorum Sensing Mediated by Acyl-Homoserine Lactone in Human Gut Microbiota (Équipe Seksik/Sokol)

Int J Mol Sci. 2022 Dec 6;23(23):15404 Intestinal dysbiosis is a key feature in the pathogenesis of inflammatory bowel disease (IBD). Acyl-homoserine lactones (AHL) are bacterial...

01 - Décembre - 2022

Diversity of the nucleic acid forms of circulating HBV in chronically infected patients and its impact on viral cycle (Équipe Gautheron/Housset)

Hepatol Int 2022 Vol. 16 Issue 6 Pages 1259-1272 BACKGROUND : Besides the prototypical hepatitis B virus (HBV) infectious particle, which contains a full-length double-stranded DNA...

01 - Décembre - 2022

Liver stiffness measurement by vibration-controlled transient elastography improves outcome prediction in primary biliary cholangitis (Équipe Gautheron/Housset)

J Hepatol 2022 Vol. 77 Issue 6 Pages 1545-1553 BACKGROUND & AIMS : Liver stiffness measurement (LSM) by vibration-controlled transient elastography (VCTE) has been shown to predict...

30 - Novembre - 2022

Effect of Flagellin Pre-Exposure on the Inflammatory and Antifungal Response of Bronchial Epithelial Cells to Fungal Pathogens (Équipe Corvol)

J Fungi (Basel). 2022 Nov 30;8(12):1268 Bronchial epithelial cells (BEC) play a crucial role in innate immunity against inhaled fungi. Indeed, in response to microorganisms, BEC synthesize...

01 - Novembre - 2022

Portal fibroblasts with mesenchymal stem cell features form a reservoir of proliferative myofibroblasts in liver fibrosis (Équipe Gautheron/Housset)

Hepatology 2022 BACKGROUND & AIMS : In liver fibrosis, myofibroblasts derive from hepatic stellate cells (HSCs) and as yet undefined mesenchymal cells. We aimed to identify portal...

21 - Octobre - 2022

The necroptosis-inducing pseudokinase mixed lineage kinase domain-like regulates the adipogenic differentiation of pre-adipocytes (Équipe Gautheron/Housset / Fève)

iScience, Volume 25, ISSUE 10, 105166, October 21, 2022 Receptor-interacting protein kinase-3 (RIPK3) and mixed lineage kinase domain- like (MLKL) proteins are key regulators of...
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