Dernières publications CRSA, Centre de Recherche de l’hôpital Saint-Antoine

09 - Juin - 2022

Deciphering pathological remodelling of the human cartilage extracellular matrix in osteoarthritis at the supramolecular level (Équipe Berenbaum)

Nanoscale 2022; 14: 8691-8708 The extracellular matrix (ECM) of articular cartilage is a three-dimensional network mainly constituted of entangled collagen fibrils and interfibrillar...

02 - Juin - 2022

Consequences of the Hsp110DE9 mutation in tumorigenesis and the 5-fluorouracil-based chemotherapy response in Msh2-deficient mice (Équipe Duval)

Cell Mol Life Sci 2022; 79: 332 Heat shock proteins (HSPs) play oncogenic roles in human tumours. We reported a somatic inactivating mutation of HSP110 (HSP110DE9) in mismatch...

01 - Juin - 2022

Fecal microbiota and bile acids in IBD patients undergoing screening for colorectal cancer (Équipe Seksik/Sokol)

Gut Microbes 2022; 14: 2078620 Due to the potential role of the gut microbiota and bile acids in the pathogenesis of both inflammatory bowel disease (IBD) and sporadic colorectal cancer, we...

28 - Mai - 2022

Loss of thymidine phosphorylase activity disrupts adipocyte differentiation and induces insulin-resistant lipoatrophic diabetes (Équipe Gautheron/Housset / Fève)

BMC Med. 2022 Mar 28;20(1):95 BACKGROUND : Thymidine phosphorylase (TP), encoded by the TYMP gene, is a cytosolic enzyme essential for the nucleotide salvage pathway. TP catalyzes the...

18 - Mai - 2022

(99m)Tc-NTP 15-5 is a companion radiotracer for assessing joint functional response to sprifermin (rhFGF-18) in a murine osteoarthritis model (Équipe Berenbaum)

Sci Rep 2022; 12: 8146 With the emergence of disease modifying osteoarthritis drugs (DMOAD), imaging methods to quantitatively demonstrate their efficacy and to monitor osteoarthritis...

11 - Mai - 2022

Human CD4+/CD8alpha+ regulatory T cells induced by Faecalibacterium prausnitzii protect against intestinal inflammation (Équipe Seksik-Sokol)

JCI Insight 2022 Faecalibacterium prausnitzii (F. prausnitzii), a dominant bacterium of the human microbiota, is decreased in patients with inflammatory bowel diseases (IBD) and exhibits...

29 - Avril - 2022

Alpha-7 Nicotinic Receptor Dampens Murine Osteoblastic Response to Inflammation and Age-Related Osteoarthritis (Équipe Berenbaum)

Front Immunol 2022; 13: 842538 Introduction : Osteoarthritis (OA) is a whole-joint disease characterized by a low-grade inflammation that is involved in both cartilage degradation and...

02 - Avril - 2022

Dental pulp stem cells as a promising model to study imprinting diseases (Équipe Netchine)

PInt J Oral Sci 2022; 14: 19 arental imprinting is an epigenetic process leading to monoallelic expression of certain genes depending on their parental origin. Imprinting diseases are...

15 - Mars - 2022

Targeting the GLP-1/GLP-1R axis to treat osteoarthritis: A new opportunity? (Équipe Berenbaum)

J Orthop Translat 2022; 32: 121-129 Osteoarthritis (OA) is a degenerative joint disease affecting millions of people worldwide. In OA, chondrocytes, synovial cells and other joint cells...

14 - Mars - 2022

WISP2/CCN5 Suppresses Vasculogenic Mimicry through Inhibition of YAP/TAZ Signaling in Breast Cancer Cells (Équipe Sabbah)

Cancers (Basel) 2022; 14 Vasculogenic mimicry (VM) formed by aggressive tumor cells to create vascular networks connected with the endothelial cells, plays an important role in breast...

Dernières publications

Publication de diverses études scientifiques