Eur J Hum Genet (2021)
Silver-Russell syndrome (SRS) is a rare imprinting disorder associated with prenatal and postnatal growth retardation. Loss of methylation (LOM) on chromosome 11p15...
Cancers (Basel) 13 (2021)
A high expression of the phosphoprotein osteopontin (OPN) has been associated with cancer progression in several tumor types, including breast cancer,...
Thromb Haemost 121 (2021): 992-1007
BACKGROUND : One year after the declaration of the coronavirus disease 2019 (COVID-19) pandemic by the World Health Organization (WHO) and despite the...
Leukemia (2021)
Myeloma is characterized by bone lesions, which are related to both an increased osteoclast activity and a defect in the differentiation of medullary mesenchymal stem cells...
Molecules 26 (2021)
There is an urgent need for specific antiviral treatments directed against SARS-CoV-2 to prevent the most severe forms of COVID-19. By drug repurposing, affordable...
Autophagy 17 (2021): 1296-1315
Mitochondria respond to many cellular functions and act as central hubs in innate immunity against viruses. This response is notably due to their role in the...
Water Res 198 (2021): 117183
The ongoing global pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been a public...
Cell Host Microbe. 2021;29(2):145-7
How gut microbes can regulate the enteric nervous system and gut-brain communications is a field of intense research. In this issue of Cell Host &...
Cell Rep. 2021;36(1):109332
Gut interleukin-17A (IL-17)-producing gammadelta T cells are tissue-resident cells that are involved in both host defense and regulation of intestinal...
Gut Microbes. 2021;13(1):1-19
The current pandemic of coronavirus disease (COVID) 2019 constitutes a global public health issue. Regarding the emerging importance of the gut-lung axis in...
Nat Rev Gastroenterol Hepatol. 2021
Faecal microbiota transplantation (FMT) is a promising therapy for chronic diseases associated with gut microbiota alterations. FMT cures 90% of...
Sci Rep. 2020;10(1):8852
The cholinergic system plays a major anti-inflammatory role in many diseases through acetylcholine (Ach) release after vagus nerve stimulation. Osteoarthritis (OA)...
Arthritis Rheumatol. 2020
OBJECTIVE : The non-neuronal cholinergic system represents non-neuronal cells that have the biochemical machinery to synthetize de novo and/or respond to...
Joint Bone Spine. 2020
OBJECTIVES : To establish recommendations for pharmacological treatment of knee osteoarthritis specific to France.
METHODS : On behalf of the French Society of...
Osteoarthritis Cartilage. 2020;28(10):1373-84
OBJECTIVE : TGFbeta is a key player in cartilage homeostasis and OA pathology. However, few data are available on the role of TGFbeta...
